Description
Piciclib Palbociclib 100mg Capsules: A Comprehensive Overview
Piciclib Palbociclib 100mg Capsules contain Palbociclib, a potent, targeted therapy drug. Doctors use this medication primarily for treating hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer. As a targeted therapy, Palbociclib works by a highly specific mechanism. It actively inhibits cyclin-dependent kinases 4 and 6 (CDK4/6). In essence, CDK4/6 are proteins that regulate the cell cycle and promote cell division. Consequently, by blocking these proteins, the drug arrests the cell cycle in the G1 phase. For this reason, it effectively slows down cancer cell growth, thereby extending progression-free survival in patients.
Usage, Administration, and Therapeutic Protocols
The medication is usually prescribed in combination with hormone therapy. For instance, a doctor may combine it with an aromatase inhibitor (like letrozole) for initial therapy in postmenopausal women. Alternatively, they may combine it with fulvestrant for women whose disease has progressed. The regimen involves taking the capsules for 21 consecutive days, followed by 7 days off, to allow for bone marrow recovery. Furthermore, the specific combination and cycle depend heavily on the patient’s menopausal status and their previous treatment history.
Manufacturing, Safety, and Monitoring
Cipla manufactures Piciclib Palbociclib 100mg Capsules. While it offers a crucial therapeutic benefit, a patient may experience some side effects. Common adverse effects include infections, fatigue, nausea, and hair thinning. However, a more serious and dose-limiting concern is neutropenia (low white blood cell count). For this reason, doctors consider periodic blood monitoring essential during treatment. To that end, routine blood tests help doctors detect neutropenia early and determine if a temporary dose interruption is necessary to manage this risk safely.
Availability & Purchase Information
Genetec Lifesciences makes Piciclib Palbociclib 100mg Capsules available. Contact us for quotations or to place an order. All products are procured through verified and authorized sources.
Disclaimer
This site provides product information for informative purposes only. The product image belongs to its respective company. Genetec Lifesciences acts as a wholesaler and distributor, not a manufacturer. We source our medicines directly from the company or authorized vendors of the company.