Description
Xbira 250mg Tablets: A Comprehensive Overview
Xbira 250mg Tablets contain Abiraterone Acetate, an oral medication classified as an androgen biosynthesis inhibitor. Doctors use this drug to treat metastatic castration-resistant prostate cancer (mCRPC) and metastatic high-risk castration-sensitive prostate cancer (mCSPC). Abiraterone works by a highly specific endocrine mechanism. It actively inhibits the CYP17 enzyme (17$\alpha$-hydroxylase/C17,20-lyase). In essence, this enzyme plays a crucial role in the biosynthesis of androgens (male hormones) in the testes, adrenal glands, and prostate tumor tissue itself. Consequently, this action dramatically lowers testosterone levels throughout the body. This deprivation effectively starves the prostate cancer cells of the androgens that fuel their growth.
Usage, Administration, and Therapeutic Protocols
A patient takes these tablets orally once daily. A crucial instruction is that Xbira must be taken on an empty stomach. This is vital because food increases its absorption significantly, potentially leading to higher drug levels and raising the risk of severe side effects. The standard protocol requires taking Xbira typically in combination with prednisone or methylprednisolone. This combination helps manage the risk of mineralocorticoid excess (like hypertension and hypokalemia) that results from inhibiting CYP17. Furthermore, consistent daily adherence to the prescribed schedule is essential for maximizing therapeutic benefits and maintaining effective androgen suppression.
Manufacturing, Safety, and Monitoring
Cipla manufactures Xbira Abiraterone 250mg Tablets. While it is a cornerstone in prostate cancer therapy, a patient may experience some side effects. Common adverse effects include hypertension (high blood pressure), hypokalemia (low potassium levels), fluid retention, and elevated liver enzymes. For this reason, doctors consider regular monitoring of blood pressure, liver function, and potassium levels essential during treatment. To that end, routine monitoring helps doctors manage potential cardiovascular and hepatic risks swiftly and safely.
Availability & Purchase Information
Genetec Lifesciences makes Xbira 250mg Tablets available. To place an order or request a quote, please contact us directly. We ensure all products are sourced from verified and authorized vendors.
Disclaimer
This site provides product information for informative purposes only. The product image belongs to its respective company. Genetec Lifesciences acts as a wholesaler and distributor, not a manufacturer. We source our medicines directly from the company or its authorized vendors.