TREXOVA Methotrexate 1g
Trexova Methotrexate 1g Injection is a medicine used for treatment of cancer in various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It may be used with other medicines as part of combination therapy.
Trexova Methotrexate 1g Injection is given under the supervision of a healthcare professional and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects.
TREXOVA 1000mg Methotrexate may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.
The most common side effects of Trexova Methotrexate 1g Injection include nausea, vomiting, loss of appetite, abdominal pain, tiredness, and mouth sores. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. Trexova Methotrexate 1g , Methotrexate is a very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these.
Before taking Trexova Methotrexate 1g Injection, tell your doctor if have stomach, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. Trexova Methotrexate 1g medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, X-rays and physical examinations both before and during treatment with this medicine.
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Indication of Trexova Methotrexate 1g Injection:
Trexova Methotrexate 1g is indicated in the treatment of gestational choriocarcinoma, chorioadenoma destruens, and hydatidiform mole.
- In acute lymphocytic leukemia, Trexova Methotrexate Injection is indicated in the prophylaxis of meningeal leukemia and is used in maintenance therapy in combination with other chemotherapeutic agents. Methotrexate is also indicated in the treatment of meningeal leukemia.
- Trexova Methotrexate Injection is used alone or in combination with other anticancer agents in the treatment of breast cancer, epidermoid cancers of the head and neck, advanced mycosis fungoides (cutaneous T cell lymphoma), and lung cancer, particularly squamous cell and small cell types. Methotrexate is also used in combination with other chemotherapeutic agents in the treatment of advanced stage non-Hodgkin’s lymphomas.
- Trexova Methotrexate Injection in high doses followed by leucovorin rescue in combination with other chemotherapeutic agents is effective in prolonging relapse-free survival in patients with non-metastatic osteosarcoma who have undergone surgical resection or amputation for the primary tumor.
- Trexova Methotrexate Injection is indicated in the symptomatic control of severe, recalcitrant, disabling psoriasis that is not adequately responsive to other forms of therapy, but only when the diagnosis has been established, as by biopsy and/or after dermatologic consultation.
Benefit of Trexova Methotrexate 1g Injection,
In Cancer
Trexova Methotrexate Injection belongs to a group of medicines called antimetabolites and is referred to as a cytotoxic. It works by slowing the growth of cancer cells in the body. It is used to treat a wide range of cancers such as acute leukemias, non-Hodgkin’s lymphoma, and solid tumors found in breast, lung, bladder, head and neck as well as cervical, ovarian and testicular cancer. It may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated
In Treatment of Rheumatoid arthritis
Trexova Methotrexate Injection belongs to a group of medicines called antimetabolites. It may be used to treat severe rheumatoid arthritis if other treatments have already been tried and have not worked. It is not a first-line treatment. It works by reducing the body’s immune system, this decreases swelling, reduces pain, stiffness, and improves function. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. Do not take more than you should. It may take several months to become fully effective.
In Treatment of Psoriasis
Trexova Methotrexate Injection belongs to a group of medicines called antimetabolites. It may be used to treat severe psoriasis when other treatments have not worked. Psoriasis is a condition where the skin cells in the body grow too quickly. Trexova Methotrexate works by killing these fast-growing cells. It is potent and very toxic medicine and you should discuss the risks and benefits with your doctor. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. Do Not take more than you should. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side Effects of Trexova Methotrexate 1g Injection
Before you can start Trexova Methotrexate Injection, your doctor will need to make sure it is the right drug for you by checking if:
- you’re pregnant or planning a family
- you’re breastfeeding
- you have an infection
- you have a liver or kidney disease
- you’ve had a recent vaccination
- you’ve had severe mouth ulcers
- you’ve had ulcers in the stomach or bowe
Trexova Methotrexate 1g Injection can sometimes cause side effects, which may include:
- feeling sick
- headaches
- vomiting
- diarrheic
- shortness of breath
- mouth ulcers
- minor hair loss and hair thinning
- rashes.
How To Use Trexova 1g Methotrexate
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
How Trexova Methotrexate 1g Injection Works
Methotrexate is an anti-cancer medication. It works by blocking an enzyme (dihydrofolate reductase) involved in DNA synthesis in cancer cells. This slows the growth of cancer cells and eventually kills them.
Safety Advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Trexova Methotrexate. Please consult your doctor.
Pregnancy
UNSAFE
Trexova Methotrexate is highly unsafe to use during pregnancy. Seek your doctor’s advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
UNSAFE
Trexova Methotrexate is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Trexova Methotrexate may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Trexova Methotrexate should be used with caution in patients with kidney disease. Dose adjustment of Methotrexate 1g Injection may be needed. Please consult your doctor.
Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Trexova Methotrexate should be used with caution in patients with liver disease. Dose adjustment of Methotrexate 1g Injection may be needed. Please consult your doctor.
Use of Methotrexate 1g Injection is not recommended in patients with severe liver disease.
Price of Trexova Methotrexate 1g in India:
Cost of Trexova Methotrexate 1g in India
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