Leucovorin calcium LUCAL is one of several active, chemically reduced derivatives of folic acid. It is useful as an antidote to drugs which act as folic acid antagonists.
Leucovorin calcium LUCALis administered at the proper time following methotrexate as part of a total chemotherapeutic plan, where it may “rescue” bone marrow and gastrointestinal mucosa cells from methotrexate.
Leucovorin Calcium 50mg/5ml
PACK :SINGLE VIAL
CELON LABS INDIA.
Leucovorin calcium LUCAL rescue is indicated after high dose methotrexate therapy in osteosarcoma Leucovorin calcium LUCAL is also indicated to diminish the toxicity and counteract the effects of impaired methotrexate elimination and of inadvertent overdosages of folic acid antagonists.
Leucovorin calcium LUCAL is indicated in the treatment of megaloblastic anemias due to folic acid deficiency when oral therapy is not feasible.
Leucovorin calcium LUCAL is also indicated for use in combination with 5-fluorouracil to prolong survival in the palliative treatment of patients with advanced colorectal cancer. Leucovorin (leucovorin calcium) should not be mixed in the same infusion as 5-fluorouracil because a precipitate may form
Folinic acid should not be administered Intrathecally (into the spinal canal) This may produce severe adverse effects or even death.
Leucovorin calcium LUCAL is to be taken strictly under Medical Supervision Only